hepatoSIGHT® for researchers

Design smarter trials. Reduce screen failures. Accelerate enrolment.

hepatoSIGHT® is a case-finding search engine that uses real-world NHS test results to help research teams plan studies, pre-qualify participants, and recruit earlier.

Liver disease trials face unique challenges with recruitment as it is often a silent disease that many do not seek care for. This means the lifesaving research into treatments and diagnostics is delayed.

hepatoSIGHT® is a case-finding search engine that enables researchers to quickly and cost-effectively identify specific cohorts of patients eligible for trial recruitment.

The system takes existing blood test results and uses simple yet powerful filters to help you find people likely to qualify for your study.

Globally, around 80% of trials fail to hit their enrolment timelines.

Why researchers use hepatoSIGHT®

Inform protocol design with real-world evidence

Understand local prevalence, phenotypes, and trends over time to shape inclusion, exclusion, and sample size with confidence

Reduce screen failures

Apply protocol criteria to historic laboratory and clinical data, exclude likely contraindications early, and send clinics a pre-qualified list

Front-load recruitment

Identify eligible people from existing records, rather than waiting for clinic flow. Move from feasibility to first consent faster

Improve demographic representation

Target cohorts by geography, deprivation, age, sex, and clinical markers to reach groups who are often under-recruited, supporting studies that better reflect the population

Works for every stage of research site

From experienced research centres to sites taking first steps, we provide templates, training, and a clear search model to maintain quality

Customisable features

Build cohorts using demographics, blood tests, calculated scores, longitudinal trends, and service use. Save and re-run searches as protocols evolve

Feasibility and mapping

Estimate the reachable pool for MASLD, MASH, and other hepatic phenotypes. View distribution across time and place to plan where recruitment effort will achieve the most impact

Cohort pre-qualification

Apply inclusion and exclusion criteria at the site level to generate lists for clinical validation and outreach

How hepatoSIGHT® works for research

Data stays in the NHS

Identifiable data remain within the host Trust research site. Predictive Health Intelligence does not receive identifiable patient data.

Define criteria

Translate protocol inclusion and exclusion into configurable filters.

Run case-finding

Search across years of results to identify people likely to be eligible.

Clinical validation

Site investigators review lists, confirm suitability, and contact participants.

Recruit and refine

Begin recruitment with a large pre-qualified list immediately.

Outcomes you can expect

Faster transition from feasibility to first patient in

Lower screen failure rates

More representative cohorts, aligned with NHS priorities on health inequalities

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